Cargando…

Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis

Liposomes containing phosphatidylserine (PS) has been used for the delivery of drugs into the intramacrophage milieu. Leishmania (L.) infantum parasites live inside macrophages and cause a fatal and neglected viscerotropic disease, with a toxic treatment. Sertraline was studied as a free formulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romanelli, Maiara Maria, da Costa-Silva, Thais Alves, Cunha-Junior, Edezio, Dias Ferreira, Daiane, Guerra, Juliana M., Galisteo, Andres Jimenez, Pinto, Erika Gracielle, Barbosa, Leandro R. S., Torres-Santos, Eduardo Caio, Tempone, Andre Gustavo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828611/ https://www.ncbi.nlm.nih.gov/pubmed/31737574 http://dx.doi.org/10.3389/fcimb.2019.00353

Ejemplares similares

Targeting intracellular Leishmania (L.) infantum with nitazoxanide entrapped into phosphatidylserine-nanoliposomes: An experimental study
por: Pinto, Erika Gracielle, et al.
Publicado: (2020)

Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study
por: Ferreira, Daiane Dias, et al.
Publicado: (2018)

Efficacy of Spironolactone Treatment in Murine Models of Cutaneous and Visceral Leishmaniasis
por: Andrade-Neto, Valter Viana, et al.
Publicado: (2021)

Biological activity and structure–activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis
por: Amaral, Maiara, et al.
Publicado: (2023)

Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B
por: Morizot, Gloria, et al.
Publicado: (2016)

Internalization of paramagnetic phosphatidylserine-containing liposomes by macrophages
por: Geelen, Tessa, et al.
Publicado: (2012)

Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis
por: Voak, Andrew A., et al.
Publicado: (2021)

Piperazine amides with desirable solubility, physicochemical and drug-like properties: Synthesis and evaluation of the anti-Trypanosoma cruzi activity
por: Varela, Marina T., et al.
Publicado: (2023)

Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging
por: Zhang, Liang, et al.
Publicado: (2016)

Visceral leishmaniasis
por: Sundar, Shyam
Publicado: (2015)

Case Report: Use of Liposomal Amphotericin B in Low Doses in Patients With Visceral Leishmaniasis
por: Ren, Danfeng, et al.
Publicado: (2021)

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice
por: Cunha-Júnior, Edézio Ferreira, et al.
Publicado: (2017)

Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritis
por: Urbano, Paulo CM, et al.
Publicado: (2015)

Pharmacodynamics and Biodistribution of Single-Dose Liposomal Amphotericin B at Different Stages of Experimental Visceral Leishmaniasis
por: Voak, Andrew A., et al.
Publicado: (2017)

Congenital Visceral Leishmaniasis
por: Boehme, Catharina C., et al.
Publicado: (2006)

Immunity to Visceral Leishmaniasis
por: Ali, Nahid, et al.
Publicado: (2012)

Treatment of Visceral Leishmaniasis
por: Moore, E M, et al.
Publicado: (2010)

Immunobiology of visceral leishmaniasis
por: Kumar, Rajiv, et al.
Publicado: (2012)

Epidemiology of visceral leishmaniasis
por: Ready, Paul D
Publicado: (2014)

Visceral leishmaniasis and HIV coinfection: current perspectives
por: Lindoso, José Angelo Lauletta, et al.
Publicado: (2018)

Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis
por: Ferreira, Carolina, et al.
Publicado: (2020)

Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes
por: Stokes, C A, et al.
Publicado: (2016)

Case Report: No Response to Liposomal Daunorubicin in a Patient with Drug-Resistant HIV-Associated Visceral Leishmaniasis
por: Gow, Nicholas J., et al.
Publicado: (2015)

Early Transcriptional Liver Signatures in Experimental Visceral Leishmaniasis
por: Palacios, Génesis, et al.
Publicado: (2021)

Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis
por: Lage, Daniela P., et al.
Publicado: (2020)

From Infection to Death: An Overview of the Pathogenesis of Visceral Leishmaniasis
por: Costa, Carlos H. N., et al.
Publicado: (2023)

The Leishmaniasis East Africa Platform (LEAP): strengthening clinical trial capacity in resource-limited countries to deliver new treatments for visceral leishmaniasis
por: Wasunna, Monique, et al.
Publicado: (2016)

Factors Associated with Visceral Leishmaniasis in the Americas: A Systematic Review and Meta-Analysis
por: Belo, Vinícius Silva, et al.
Publicado: (2013)

Relationship of Serum Antileishmanial Antibody With Development of Visceral Leishmaniasis, Post-kala-azar Dermal Leishmaniasis and Visceral Leishmaniasis Relapse
por: Mondal, Dinesh, et al.
Publicado: (2019)

Visceral Leishmaniasis Treatment, Italy
por: Gradoni, Luigi, et al.
Publicado: (2003)

The reemergence of visceral leishmaniasis in Brazil.
por: Arias, J R, et al.
Publicado: (1996)

Drug Resistance in Visceral Leishmaniasis
por: Maltezou, Helena C.
Publicado: (2010)

Is visceral leishmaniasis a sepsis or not?
por: Puca, E, et al.
Publicado: (2012)

Epidemiology of Visceral Leishmaniasis in Georgia
por: Babuadze, Giorgi, et al.
Publicado: (2014)

Therapeutic Options for Visceral Leishmaniasis
por: Monge-Maillo, Begoña, et al.
Publicado: (2013)

Visceral leishmaniasis with Roth spots
por: Meena, Jagdish, et al.
Publicado: (2014)

Epidemiology of visceral leishmaniasis in Georgia
por: Kokaia, Nora, et al.
Publicado: (2017)

The kinetoplast in the diagnosis of visceral leishmaniasis
por: Murray, Henry W.
Publicado: (2022)

Therapeutic effect of ursolic acid in experimental visceral leishmaniasis
por: Jesus, Jéssica A., et al.
Publicado: (2016)

Association of Liposome-Encapsulated Trivalent Antimonial with Ascorbic Acid: An Effective and Safe Strategy in the Treatment of Experimental Visceral Leishmaniasis
por: Castro, Renata A. O., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fsmsg1lf58v13i8jo19afm247n