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Cerebrospinal Fluid Drug Concentrations and Clinical Outcome of Patients with Neoplastic Meningitis Treated with Liposomal Cytarabine

BACKGROUND AND OBJECTIVE: Liposomal cytarabine is a slow-release formulation for intrathecal application in patients with neoplastic meningitis. Although standard dosing intervals range from 2 to 4 weeks, it is unclear whether sustained cytotoxic cerebrospinal fluid (CSF) concentrations can be achie...

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Detalles Bibliográficos
Autores principales: Bohn, Jan-Paul, Reinstadler, Vera, Pall, Georg, Stockhammer, Günther, Steurer, Michael, Oberacher, Herbert, Wolf, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828631/
https://www.ncbi.nlm.nih.gov/pubmed/31435852
http://dx.doi.org/10.1007/s13318-019-00572-w