Astrocyte Infection Is Required for Retrovirus-Induced Spongiform Neurodegeneration Despite Suppressed Viral Protein Expression

The ability of retroviruses (RVs) to cause neurodegeneration is critically dependent upon two activities of the envelope protein (Env). First, Env facilitates viral genome delivery to CNS target cells through receptor binding and membrane fusion. Second, Env expression within one or more targets ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Cardona, Sandra M., Dunphy, Jaclyn M., Das, Alvin S., Lynch, Connor R., Lynch, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828646/
https://www.ncbi.nlm.nih.gov/pubmed/31736699
http://dx.doi.org/10.3389/fnins.2019.01166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828646/
https://www.ncbi.nlm.nih.gov/pubmed/31736699
http://dx.doi.org/10.3389/fnins.2019.01166

Ejemplares similares