A New Strategy for Identifying Mechanisms of Drug-drug Interaction Using Transcriptome Analysis: Compound Kushen Injection as a Proof of Principle

Drug-drug interactions (DDIs), especially with herbal medicines, are complex, making it difficult to identify potential molecular mechanisms and targets. We introduce a workflow to carry out DDI research using transcriptome analysis and interactions of a complex herbal mixture, Compound Kushen Injec...

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Detalles Bibliográficos
Autores principales: Shen, Hanyuan, Qu, Zhipeng, Harata-Lee, Yuka, Cui, Jian, Aung, Thazin Nwe, Wang, Wei, Kortschak, R. Daniel, Adelson, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828681/
https://www.ncbi.nlm.nih.gov/pubmed/31685921
http://dx.doi.org/10.1038/s41598-019-52375-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828681/
https://www.ncbi.nlm.nih.gov/pubmed/31685921
http://dx.doi.org/10.1038/s41598-019-52375-3

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