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A New Strategy for Identifying Mechanisms of Drug-drug Interaction Using Transcriptome Analysis: Compound Kushen Injection as a Proof of Principle
Drug-drug interactions (DDIs), especially with herbal medicines, are complex, making it difficult to identify potential molecular mechanisms and targets. We introduce a workflow to carry out DDI research using transcriptome analysis and interactions of a complex herbal mixture, Compound Kushen Injec...
Autores principales: | Shen, Hanyuan, Qu, Zhipeng, Harata-Lee, Yuka, Cui, Jian, Aung, Thazin Nwe, Wang, Wei, Kortschak, R. Daniel, Adelson, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828681/ https://www.ncbi.nlm.nih.gov/pubmed/31685921 http://dx.doi.org/10.1038/s41598-019-52375-3 |
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