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Translating Systems Medicine Into Clinical Practice: Examples From Pulmonary Medicine With Genetic Disorders, Infections, Inflammations, Cancer Genesis, and Treatment Implication of Molecular Alterations in Non-small-cell Lung Cancers and Personalized Medicine

Non-small-cell lung cancers (NSCLC) represent 85% of all lung cancers, with adenocarcinoma as the most common subtype. Since the 2000's, the discovery of molecular alterations including epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements togethe...

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Detalles Bibliográficos
Autores principales: Pinsolle, Julian, McLeer-Florin, Anne, Giaj Levra, Matteo, de Fraipont, Florence, Emprou, Camille, Gobbini, Elisa, Toffart, Anne-Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828737/
https://www.ncbi.nlm.nih.gov/pubmed/31737634
http://dx.doi.org/10.3389/fmed.2019.00233