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A Study Comparing the Effects of Targeted Intra-Arterial and Systemic Chemotherapy in an Orthotopic Mouse Model of Pancreatic Cancer

Systemic chemotherapy is the first line treatment for patients with unresectable pancreatic cancer, however, insufficient drug delivery to the pancreas is a major problem resulting in poor outcomes. We evaluated the therapeutic effects of targeted intra-arterial (IA) delivery of gemcitabine directly...

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Detalles Bibliográficos
Autores principales: Rezaee, Melika, Wang, Jing, Razavi, Mehdi, Ren, Gang, Zheng, Fengyan, Hussein, Ahmed, Ullah, Mujib, Thakor, Avnesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828954/
https://www.ncbi.nlm.nih.gov/pubmed/31685925
http://dx.doi.org/10.1038/s41598-019-52490-1