Evaluation of antibodies for western blot analysis of frataxin protein isoforms

Frataxin is the protein that is down-regulated in Friedreich ataxia (FRDA), an autosomal recessive genetic disease caused by an intronic GAA repeat expansion in intron-1 of the FXN gene. The GAA repeats result in epigenetic silencing of the FXN gene and reduced expression of the cytosolic full-lengt...

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Detalles Bibliográficos
Autores principales: Weng, Liwei, Wang, Qingqing, Yu, Sixiang, Yang, Xiaolu, Lynch, David R., Mesaros, Clementina, Blair, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829029/
https://www.ncbi.nlm.nih.gov/pubmed/31279523
http://dx.doi.org/10.1016/j.jim.2019.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829029/
https://www.ncbi.nlm.nih.gov/pubmed/31279523
http://dx.doi.org/10.1016/j.jim.2019.07.001

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