Ubiquitin E3 Ligase Pellino-1 Inhibits IL-10-mediated M2c Polarization of Macrophages, Thereby Suppressing Tumor Growth

Pellino-1 is a ubiquitin (Ub) E3 ligase that plays a role in M1, but not M2a polarization of macrophages. However, it is unknown whether Pellino-1 regulates IL-10-mediated M2c polarization of macrophages. Here, we found that Pellino-1 attenuated tumor growth by inhibiting M2c polarization of macroph...

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Detalles Bibliográficos
Autores principales: Kim, Donghyun, Koh, Jaemoon, Ko, Jae Sung, Kim, Hye Young, Lee, Ho, Chung, Doo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829073/
https://www.ncbi.nlm.nih.gov/pubmed/31720043
http://dx.doi.org/10.4110/in.2019.19.e32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829073/
https://www.ncbi.nlm.nih.gov/pubmed/31720043
http://dx.doi.org/10.4110/in.2019.19.e32

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