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Hypoxia Induced Heparan Sulfate Primes the Extracellular Matrix for Endothelial Cell Recruitment by Facilitating VEGF-Fibronectin Interactions

Vascular endothelial growth factor-A (VEGF) is critical for the development, growth, and survival of blood vessels. Retinal pigmented epithelial (RPE) cells are a major source of VEGF in the retina, with evidence that the extracellular matrix (ECM)-binding forms are particularly important. VEGF asso...

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Detalles Bibliográficos
Autores principales: Buczek-Thomas, Jo Ann, Rich, Celeste B., Nugent, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829205/
https://www.ncbi.nlm.nih.gov/pubmed/31614727
http://dx.doi.org/10.3390/ijms20205065