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Simple In-House Fabrication of Microwells for Generating Uniform Hepatic Multicellular Cancer Aggregates and Discovering Novel Therapeutics

Three-dimensional (3D) cell culture models have become powerful tools because they better simulate the in vivo pathophysiological microenvironment than traditional two-dimensional (2D) monolayer cultures. Tumor cells cultured in a 3D system as multicellular cancer aggregates (MCAs) recapitulate seve...

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Detalles Bibliográficos
Autores principales: Chiu, Chiao-Yi, Chen, Ying-Chi, Wu, Kuang-Wei, Hsu, Wen-Chien, Lin, Hong-Ping, Chang, Hsien-Chang, Lee, Yung-Chun, Wang, Yang-Kao, Tu, Ting-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829256/
https://www.ncbi.nlm.nih.gov/pubmed/31614495
http://dx.doi.org/10.3390/ma12203308