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Methionine Adenosyltransferase 1a (MAT1A) Enhances Cell Survival During Chemotherapy Treatment and is Associated with Drug Resistance in Bladder Cancer PDX Mice

Bladder cancer is among the top ten most common cancers, with about ~380,000 new cases and ~150,000 deaths per year worldwide. Tumor relapse following chemotherapy treatment has long been a significant challenge towards completely curing cancer. We have utilized a patient-derived bladder cancer xeno...

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Detalles Bibliográficos
Autores principales: Martin, Kelly A., Hum, Nicholas R., Sebastian, Aimy, He, Wei, Siddiqui, Salma, Ghosh, Paramita M., Pan, Chong-xian, de Vere White, Ralph, Loots, Gabriela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829260/
https://www.ncbi.nlm.nih.gov/pubmed/31600961
http://dx.doi.org/10.3390/ijms20204983