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Involvement of Progranulin and Granulin Expression in Inflammatory Responses after Cerebral Ischemia

Progranulin (PGRN) plays a crucial role in diverse biological processes, including cell proliferation and embryonic development. PGRN can be cleaved by neutrophil elastase to release granulin (GRN). PGRN has been found to inhibit inflammation. Whereas, GRN plays a role as a pro-inflammatory factor....

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Detalles Bibliográficos
Autores principales: Horinokita, Ichiro, Hayashi, Hideki, Oteki, Rika, Mizumura, Risa, Yamaguchi, Tatsuaki, Usui, Akane, Yuan, Bo, Takagi, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829276/
https://www.ncbi.nlm.nih.gov/pubmed/31640144
http://dx.doi.org/10.3390/ijms20205210