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Involvement of Progranulin and Granulin Expression in Inflammatory Responses after Cerebral Ischemia
Progranulin (PGRN) plays a crucial role in diverse biological processes, including cell proliferation and embryonic development. PGRN can be cleaved by neutrophil elastase to release granulin (GRN). PGRN has been found to inhibit inflammation. Whereas, GRN plays a role as a pro-inflammatory factor....
Autores principales: | Horinokita, Ichiro, Hayashi, Hideki, Oteki, Rika, Mizumura, Risa, Yamaguchi, Tatsuaki, Usui, Akane, Yuan, Bo, Takagi, Norio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829276/ https://www.ncbi.nlm.nih.gov/pubmed/31640144 http://dx.doi.org/10.3390/ijms20205210 |
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