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The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Plasmodium falciparum Gametocyte Development and Transmission

Transmission of the malaria parasite Plasmodium falciparum from the human to the mosquito is initiated by specialized sexual cells, the gametocytes. In the human, gametocytes are formed in response to stress signals and following uptake by a blood-feeding Anopheles mosquito initiate sexual reproduct...

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Detalles Bibliográficos
Autores principales: Ngwa, Che Julius, Kiesow, Meike Jutta, Orchard, Lindsey Marie, Farrukh, Afia, Llinás, Manuel, Pradel, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829282/
https://www.ncbi.nlm.nih.gov/pubmed/31615031
http://dx.doi.org/10.3390/ijms20205087