Novel Peptidomic Approach for Identification of Low and High Molecular Weight Tauopathy Peptides Following Calpain Digestion, and Primary Culture Neurotoxic Challenges

Tauopathy is a class of a neurodegenerative disorder linked with tau hyperphosphorylation, proteolysis, and aggregation. Tau can be subjected to proteolysis upon calpain activation in Alzheimer disease (AD), and traumatic brain injury (TBI). We and others have extensively researched calpain-mediated...

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Detalles Bibliográficos
Autores principales: Yadikar, Hamad, Johnson, Connor, Pafundi, Niko, Mouhawasse, Edwin, Nguyen, Lynn, Torres, Isabel, Kurup, Milin, Yang, Zhihui, Kobeissy, Firas, Yost, Richard, Wang, Kevin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829287/
https://www.ncbi.nlm.nih.gov/pubmed/31640160
http://dx.doi.org/10.3390/ijms20205213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829287/
https://www.ncbi.nlm.nih.gov/pubmed/31640160
http://dx.doi.org/10.3390/ijms20205213

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