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Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action

The formation of multienzymatic complexes allows for the fine tuning of many aspects of enzymatic functions, such as efficiency, localization, stability, and moonlighting. Here, we investigated, in solution, the structure of bacterial cysteine synthase (CS) complex. CS is formed by serine acetyltran...

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Detalles Bibliográficos
Autores principales: Rosa, Brenda, Marchetti, Marialaura, Paredi, Gianluca, Amenitsch, Heinz, Franko, Nina, Benoni, Roberto, Giabbai, Barbara, De Marino, Maria Giovanna, Mozzarelli, Andrea, Ronda, Luca, Storici, Paola, Campanini, Barbara, Bettati, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829319/
https://www.ncbi.nlm.nih.gov/pubmed/31640223
http://dx.doi.org/10.3390/ijms20205219