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MicroRNA-29a Counteracts Glucocorticoid Induction of Bone Loss through Repressing TNFSF13b Modulation of Osteoclastogenesis

Glucocorticoid excess escalates osteoclastic resorption, accelerating bone mass loss and microarchitecture damage, which ramps up osteoporosis development. MicroRNA-29a (miR-29a) regulates osteoblast and chondrocyte function; however, the action of miR-29a to osteoclastic activity in the glucocortic...

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Detalles Bibliográficos
Autores principales: Wu, Re-Wen, Lian, Wei-Shiung, Chen, Yu-Shan, Kuo, Chung-Wen, Ke, Huei-Ching, Hsieh, Chin-Kuei, Wang, Shao-Yu, Ko, Jih-Yang, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829322/
https://www.ncbi.nlm.nih.gov/pubmed/31627291
http://dx.doi.org/10.3390/ijms20205141