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Targeting NRF2 for the Treatment of Friedreich’s Ataxia: A Comparison among Drugs

NRF2 (Nuclear factor Erythroid 2-related Factor 2) signaling is impaired in Friedreich’s Ataxia (FRDA), an autosomal recessive disease characterized by progressive nervous system damage and degeneration of nerve fibers in the spinal cord and peripheral nerves. The loss of frataxin in patients result...

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Detalles Bibliográficos
Autores principales: Petrillo, Sara, D’Amico, Jessica, La Rosa, Piergiorgio, Bertini, Enrico Silvio, Piemonte, Fiorella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829337/
https://www.ncbi.nlm.nih.gov/pubmed/31640150
http://dx.doi.org/10.3390/ijms20205211