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Targeting NRF2 for the Treatment of Friedreich’s Ataxia: A Comparison among Drugs
NRF2 (Nuclear factor Erythroid 2-related Factor 2) signaling is impaired in Friedreich’s Ataxia (FRDA), an autosomal recessive disease characterized by progressive nervous system damage and degeneration of nerve fibers in the spinal cord and peripheral nerves. The loss of frataxin in patients result...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829337/ https://www.ncbi.nlm.nih.gov/pubmed/31640150 http://dx.doi.org/10.3390/ijms20205211 |