Spontaneous Development of Dental Dysplasia in Aged Parp-1 Knockout Mice

Poly(ADP-ribose) polymerase (Parp)-1 catalyzes polyADP-ribosylation using NAD(+) and is involved in the DNA damage response, genome stability, and transcription. In this study, we demonstrated that aged Parp-1(−/−) mouse incisors showed more frequent dental dysplasia in both ICR/129Sv mixed backgrou...

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Detalles Bibliográficos
Autores principales: Fujihara, Hisako, Nozaki, Tadashige, Tsutsumi, Masahiro, Isumi, Mayu, Shimoda, Shinji, Hamada, Yoshiki, Masutani, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829344/
https://www.ncbi.nlm.nih.gov/pubmed/31569682
http://dx.doi.org/10.3390/cells8101157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829344/
https://www.ncbi.nlm.nih.gov/pubmed/31569682
http://dx.doi.org/10.3390/cells8101157

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