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Spontaneous Development of Dental Dysplasia in Aged Parp-1 Knockout Mice

Poly(ADP-ribose) polymerase (Parp)-1 catalyzes polyADP-ribosylation using NAD(+) and is involved in the DNA damage response, genome stability, and transcription. In this study, we demonstrated that aged Parp-1(−/−) mouse incisors showed more frequent dental dysplasia in both ICR/129Sv mixed backgrou...

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Detalles Bibliográficos
Autores principales:	Fujihara, Hisako, Nozaki, Tadashige, Tsutsumi, Masahiro, Isumi, Mayu, Shimoda, Shinji, Hamada, Yoshiki, Masutani, Mitsuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829344/ https://www.ncbi.nlm.nih.gov/pubmed/31569682 http://dx.doi.org/10.3390/cells8101157

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