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Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction

In the era of combined antiretroviral therapy (cART), as infected individuals continue to have longer lifespans, there is also an increased prevalence of HIV-associated neurocognitive disorders (HAND). Inflammation is one of the underlying features of HAND, with the role of viral proteins and antire...

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Detalles Bibliográficos
Autores principales: Tripathi, Ashutosh, Thangaraj, Annadurai, Chivero, Ernest T., Periyasamy, Palsamy, Callen, Shannon, Burkovetskaya, Maria E., Guo, Ming-Lei, Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829395/
https://www.ncbi.nlm.nih.gov/pubmed/31569373
http://dx.doi.org/10.3390/cells8101168