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Analysis of Procollagen C-Proteinase Enhancer-1/Glycosaminoglycan Binding Sites and of the Potential Role of Calcium Ions in the Interaction

In this study, we characterize the interactions between the extracellular matrix protein, procollagen C-proteinase enhancer-1 (PCPE-1), and glycosaminoglycans (GAGs), which are linear anionic periodic polysaccharides. We applied molecular modeling approaches to build a structural model of full-lengt...

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Detalles Bibliográficos
Autores principales: Potthoff, Jan, Bojarski, Krzysztof K., Kohut, Gergely, Lipska, Agnieszka G., Liwo, Adam, Kessler, Efrat, Ricard-Blum, Sylvie, Samsonov, Sergey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829435/
https://www.ncbi.nlm.nih.gov/pubmed/31658765
http://dx.doi.org/10.3390/ijms20205021