The Effects of TGF-β Signaling on Cancer Cells and Cancer Stem Cells in the Bone Microenvironment

Background: Transforming growth factor-β (TGF-β) plays a key role in bone metastasis formation; we hypothesized the possible involvement of TGF-β in the induction of cancer stem cells (CSCs) in the bone microenvironment (micro-E), which may be responsible for chemo-resistance. Methods: Mouse mammary...

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Detalles Bibliográficos
Autores principales: Futakuchi, Mitsuru, Lami, Kris, Tachibana, Yuri, Yamamoto, Yukari, Furukawa, Masahiro, Fukuoka, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829436/
https://www.ncbi.nlm.nih.gov/pubmed/31619018
http://dx.doi.org/10.3390/ijms20205117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829436/
https://www.ncbi.nlm.nih.gov/pubmed/31619018
http://dx.doi.org/10.3390/ijms20205117

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