Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization

Inflammatory activation of astroglia adds to the pathology of various neurological diseases. Astrocytes respond to microglia-derived cytokines such as interleukin-1α (IL-1α) with enhanced inflammatory signaling. This provokes pro-inflammatory gene expression of, among others, the eicosanoid-generati...

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Detalles Bibliográficos
Autores principales: Astakhova, Alina, Chistyakov, Dmitry, Thomas, Dominique, Geisslinger, Gerd, Brüne, Bernhard, Sergeeva, Marina, Namgaladze, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829456/
https://www.ncbi.nlm.nih.gov/pubmed/31581537
http://dx.doi.org/10.3390/cells8101185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829456/
https://www.ncbi.nlm.nih.gov/pubmed/31581537
http://dx.doi.org/10.3390/cells8101185

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