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Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE (-/-) Mice

Chronic exposure to low-dose ionizing radiation is associated with an increased risk of cardiovascular disease. Alteration in energy metabolism has been suggested to contribute to radiation-induced heart pathology, mitochondrial dysfunction being a hallmark of this disease. The goal of this study wa...

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Detalles Bibliográficos
Autores principales: Barjaktarovic, Zarko, Merl-Pham, Juliane, Braga-Tanaka, Ignacia, Tanaka, Satoshi, Hauck, Stefanie M., Saran, Anna, Mancuso, Mariateresa, Atkinson, Michael J., Tapio, Soile, Azimzadeh, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829468/
https://www.ncbi.nlm.nih.gov/pubmed/31652604
http://dx.doi.org/10.3390/ijms20205239