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Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from Toxoplasma gondii

The microneme organelles of Toxoplasma gondii tachyzoites release protein complexes (MICs), including one composed of the transmembrane protein MIC6 plus MIC1 and MIC4. In this complex, carbohydrate recognition domains of MIC1 and MIC4 are exposed and interact with terminal sialic acid and galactose...

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Detalles Bibliográficos
Autores principales: Costa Mendonça-Natividade, Flávia, Duque Lopes, Carla, Ricci-Azevedo, Rafael, Sardinha-Silva, Aline, Figueiredo Pinzan, Camila, Paiva Alegre-Maller, Ana Claudia, L. Nohara, Lilian, B. Carneiro, Alan, Panunto-Castelo, Ademilson, C. Almeida, Igor, Roque-Barreira, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829480/
https://www.ncbi.nlm.nih.gov/pubmed/31658592
http://dx.doi.org/10.3390/ijms20205001