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Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from Toxoplasma gondii
The microneme organelles of Toxoplasma gondii tachyzoites release protein complexes (MICs), including one composed of the transmembrane protein MIC6 plus MIC1 and MIC4. In this complex, carbohydrate recognition domains of MIC1 and MIC4 are exposed and interact with terminal sialic acid and galactose...
Autores principales: | Costa Mendonça-Natividade, Flávia, Duque Lopes, Carla, Ricci-Azevedo, Rafael, Sardinha-Silva, Aline, Figueiredo Pinzan, Camila, Paiva Alegre-Maller, Ana Claudia, L. Nohara, Lilian, B. Carneiro, Alan, Panunto-Castelo, Ademilson, C. Almeida, Igor, Roque-Barreira, Maria Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829480/ https://www.ncbi.nlm.nih.gov/pubmed/31658592 http://dx.doi.org/10.3390/ijms20205001 |
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