Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome

Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic drugs. In recent years, zebrafish disease models with Scn1Lab sodium channel deficiency have been generated to seek novel anti-epileptic drug candidates, some of which are currently undergoing clini...

Descripción completa

Detalles Bibliográficos
Autores principales: Brenet, Alexandre, Hassan-Abdi, Rahma, Somkhit, Julie, Yanicostas, Constantin, Soussi-Yanicostas, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829503/
https://www.ncbi.nlm.nih.gov/pubmed/31590334
http://dx.doi.org/10.3390/cells8101199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829503/
https://www.ncbi.nlm.nih.gov/pubmed/31590334
http://dx.doi.org/10.3390/cells8101199

Ejemplares similares