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Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome
Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic drugs. In recent years, zebrafish disease models with Scn1Lab sodium channel deficiency have been generated to seek novel anti-epileptic drug candidates, some of which are currently undergoing clini...
Autores principales: | Brenet, Alexandre, Hassan-Abdi, Rahma, Somkhit, Julie, Yanicostas, Constantin, Soussi-Yanicostas, Nadia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829503/ https://www.ncbi.nlm.nih.gov/pubmed/31590334 http://dx.doi.org/10.3390/cells8101199 |
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