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Effects of Membrane and Biological Target on the Structural and Allosteric Properties of Recoverin: A Computational Approach

Recoverin (Rec) is a prototypical calcium sensor protein primarily expressed in the vertebrate retina. The binding of two Ca(2+) ions to the functional EF-hand motifs induces the extrusion of a myristoyl group that increases the affinity of Rec for the membrane and leads to the formation of a comple...

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Detalles Bibliográficos
Autores principales: Borsatto, Alberto, Marino, Valerio, Abrusci, Gianfranco, Lattanzi, Gianluca, Dell’Orco, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829511/
https://www.ncbi.nlm.nih.gov/pubmed/31658639
http://dx.doi.org/10.3390/ijms20205009