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Effects of Membrane and Biological Target on the Structural and Allosteric Properties of Recoverin: A Computational Approach
Recoverin (Rec) is a prototypical calcium sensor protein primarily expressed in the vertebrate retina. The binding of two Ca(2+) ions to the functional EF-hand motifs induces the extrusion of a myristoyl group that increases the affinity of Rec for the membrane and leads to the formation of a comple...
Autores principales: | Borsatto, Alberto, Marino, Valerio, Abrusci, Gianfranco, Lattanzi, Gianluca, Dell’Orco, Daniele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829511/ https://www.ncbi.nlm.nih.gov/pubmed/31658639 http://dx.doi.org/10.3390/ijms20205009 |
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