Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells

The loss of mitochondrial function impairs intracellular energy production and potentially results in chronic liver disease. Increasing evidence suggests that mitochondrial dysfunction in hepatocytes contributes to the activation of hepatic stellate cells (HSCs), thereby resulting in hepatic fibroge...

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Detalles Bibliográficos
Autores principales: Hur, Wonhee, Kang, Byung Yoon, Kim, Sung Min, Lee, Gil Won, Kim, Jung-Hee, Nam, Min-Kyung, Rhim, Hyangshuk, Yoon, Seung Kew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829542/
https://www.ncbi.nlm.nih.gov/pubmed/31547195
http://dx.doi.org/10.3390/cells8101119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829542/
https://www.ncbi.nlm.nih.gov/pubmed/31547195
http://dx.doi.org/10.3390/cells8101119

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