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Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells
The loss of mitochondrial function impairs intracellular energy production and potentially results in chronic liver disease. Increasing evidence suggests that mitochondrial dysfunction in hepatocytes contributes to the activation of hepatic stellate cells (HSCs), thereby resulting in hepatic fibroge...
Autores principales: | Hur, Wonhee, Kang, Byung Yoon, Kim, Sung Min, Lee, Gil Won, Kim, Jung-Hee, Nam, Min-Kyung, Rhim, Hyangshuk, Yoon, Seung Kew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829542/ https://www.ncbi.nlm.nih.gov/pubmed/31547195 http://dx.doi.org/10.3390/cells8101119 |
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