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Programmed Death Ligand 1 Indicates Pre-Existing Adaptive Immune Response by Tumor-Infiltrating CD8(+) T Cells in Non-Small Cell Lung Cancer

Aberrant expression of programmed death ligand 1 (PD-L1) on tumor cells impedes antitumor immunity and instigates immune evasion. The remarkable efficacy of immune checkpoint blockade has been confirmed in various solid tumors. However, the correlation between PD-L1 expression and host immunological...

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Detalles Bibliográficos
Autores principales: Li, Yi-Ming, Yu, Jing-Min, Liu, Zhen-Yu, Yang, Hai-Jiao, Tang, Juan, Chen, Zhi-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829548/
https://www.ncbi.nlm.nih.gov/pubmed/31627272
http://dx.doi.org/10.3390/ijms20205138