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Effects of FGF14 and Na(V)β4 deletion on transient and resurgent Na current in cerebellar Purkinje neurons

Voltage-gated Na channels of Purkinje cells are specialized to maintain high availability during high-frequency repetitive firing. They enter fast-inactivated states relatively slowly and undergo a voltage-dependent open-channel block by an intracellular protein (or proteins) that prevents stable fa...

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Detalles Bibliográficos
Autores principales: White, Hayley V., Brown, Spencer T., Bozza, Thomas C., Raman, Indira M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829560/
https://www.ncbi.nlm.nih.gov/pubmed/31558566
http://dx.doi.org/10.1085/jgp.201912390