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miR-7 Knockdown by Peptide Nucleic Acids in the Ascidian Ciona intestinalis

Peptide Nucleic Acids (PNAs) are synthetic mimics of natural oligonucleotides, which bind complementary DNA/RNA strands with high sequence specificity. They display numerous advantages, but in vivo applications are still rare. One of the main drawbacks of PNAs application is the poor cellular uptake...

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Detalles Bibliográficos
Autores principales: Mercurio, Silvia, Cauteruccio, Silvia, Manenti, Raoul, Candiani, Simona, Scarì, Giorgio, Licandro, Emanuela, Pennati, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829576/
https://www.ncbi.nlm.nih.gov/pubmed/31623150
http://dx.doi.org/10.3390/ijms20205127