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Calcium Dyshomeostasis and Lysosomal Ca(2+) Dysfunction in Amyotrophic Lateral Sclerosis
Recent findings in the understanding of amyotrophic lateral sclerosis (ALS) revealed that alteration in calcium (Ca(2+)) homeostasis may largely contribute to motor neuron demise. A large part of these alterations is due to dysfunctional Ca(2+)-storing organelles, including the endoplasmic reticulum...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829585/ https://www.ncbi.nlm.nih.gov/pubmed/31597311 http://dx.doi.org/10.3390/cells8101216 |