Calcium Dyshomeostasis and Lysosomal Ca(2+) Dysfunction in Amyotrophic Lateral Sclerosis

Recent findings in the understanding of amyotrophic lateral sclerosis (ALS) revealed that alteration in calcium (Ca(2+)) homeostasis may largely contribute to motor neuron demise. A large part of these alterations is due to dysfunctional Ca(2+)-storing organelles, including the endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Tedeschi, Valentina, Petrozziello, Tiziana, Secondo, Agnese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829585/
https://www.ncbi.nlm.nih.gov/pubmed/31597311
http://dx.doi.org/10.3390/cells8101216

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