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Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells

Host conditioning has emerged as an important component of effective adoptive cell transfer–based immunotherapy for cancer. High levels of IL-1β are induced by host conditioning, but its impact on the antitumor function of T cells remains unclear. We found that the administration of IL-1β increased...

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Detalles Bibliográficos
Autores principales: Lee, Ping-Hsien, Yamamoto, Tori N., Gurusamy, Devikala, Sukumar, Madhusudhanan, Yu, Zhiya, Hu-Li, Jane, Kawabe, Takeshi, Gangaplara, Arunakumar, Kishton, Rigel J., Henning, Amanda N., Vodnala, Suman K., Germain, Ronald N., Paul, William E., Restifo, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829590/
https://www.ncbi.nlm.nih.gov/pubmed/31405895
http://dx.doi.org/10.1084/jem.20181218