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Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

Transendothelial migration (TEM) of leukocytes across the endothelium is critical for inflammation. In the endothelium, TEM requires the coordination of membrane movements and cytoskeletal interactions, including, prominently, recruitment of the lateral border recycling compartment (LBRC). The scaff...

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Detalles Bibliográficos
Autores principales: Sullivan, David P., Dalal, Prarthana J., Jaulin, Fanny, Sacks, David B., Kreitzer, Geri, Muller, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829592/
https://www.ncbi.nlm.nih.gov/pubmed/31395618
http://dx.doi.org/10.1084/jem.20190008