Increased Regeneration Following Stress-Induced Lung Injury in Bleomycin-Treated Chimeric Mice with CD44 Knockout Mesenchymal Cells

CD44, an adhesion-molecule promoting cell-migration, is shown here to increase in stress conditions following bleomycin-induced apoptosis in alveolar epithelial cells (AECs), a main target of lung injury. In vivo, it inhibits tissue regeneration and leads to fibrosis. We show that some AECs survive...

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Detalles Bibliográficos
Autores principales: Petukhov, Dmytro, Richter-Dayan, Mark, Fridlender, Zvi, Breuer, Raphael, Wallach-Dayan, Shulamit B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829612/
https://www.ncbi.nlm.nih.gov/pubmed/31591327
http://dx.doi.org/10.3390/cells8101211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829612/
https://www.ncbi.nlm.nih.gov/pubmed/31591327
http://dx.doi.org/10.3390/cells8101211

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