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Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection

Background: Schistosomiasis is an immunopathogenic disease in which Th17 cells play vital roles. Hepatic granuloma formation and subsequent fibrosis are its main pathologic manifestations and the leading causes of hepatic cirrhosis, and effective therapeutic interventions are lacking. In this study,...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Yang, Yingying, Mei, Congjin, Dong, Panpan, Mu, Shasha, Wu, Hongchu, Zhou, Yonghua, Zheng, Yi, Guo, Fukun, Yang, Jun-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829618/
https://www.ncbi.nlm.nih.gov/pubmed/31623153
http://dx.doi.org/10.3390/cells8101262