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An RBPJ-Drosophila Model Reveals Dependence of RBPJ Protein Stability on the Formation of Transcription–Regulator Complexes

Notch signaling activity governs widespread cellular differentiation in higher animals, including humans, and is involved in several congenital diseases and different forms of cancer. Notch signals are mediated by the transcriptional regulator RBPJ in a complex with activated Notch (NICD). Analysis...

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Detalles Bibliográficos
Autores principales: Gahr, Bernd M., Brändle, Franziska, Zimmermann, Mirjam, Nagel, Anja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829621/
https://www.ncbi.nlm.nih.gov/pubmed/31615108
http://dx.doi.org/10.3390/cells8101252