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Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy

Acute myeloid leukemia (AML) is an aggressive malignancy, and many elderly/unfit patients cannot receive intensive and potentially curative therapy. These patients receive low-toxicity disease-stabilizing treatment. The combination of all-trans retinoic acid (ATRA) and the histone deacetylase inhibi...

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Detalles Bibliográficos
Autores principales: Grønningsæter, Ida Sofie, Fredly, Hanne Kristin, Gjertsen, Bjørn Tore, Hatfield, Kimberley Joanne, Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829623/
https://www.ncbi.nlm.nih.gov/pubmed/31658693
http://dx.doi.org/10.3390/cells8101229