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Genome-Wide Mapping Defines a Role for C/EBPβ and c-Jun in Non-Canonical Cyclic AMP Signalling

The novel exchange protein activated by cyclic AMP (EPAC1) activator, I942, induces expression of the suppressor of cytokine signalling 3 (SOCS3) gene, thereby inhibiting interleukin 6 (IL6) inflammatory processes in human umbilical vein endothelial cells (HUVECs). Here we use RNA-SEQ and ChIP-SEQ t...

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Detalles Bibliográficos
Autores principales: Wiejak, Jolanta, van Basten, Boy, Hamilton, Graham, Yarwood, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829624/
https://www.ncbi.nlm.nih.gov/pubmed/31615122
http://dx.doi.org/10.3390/cells8101253