Cargando…
New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells
Protein and membrane trafficking pathways are critical for cell and tissue homeostasis. Traditional genetic and biochemical approaches have shed light on basic principles underlying these processes. However, the list of factors required for secretory pathway function remains incomplete, and mechanis...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829651/ https://www.ncbi.nlm.nih.gov/pubmed/31488582 http://dx.doi.org/10.1083/jcb.201902028 |