New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

Protein and membrane trafficking pathways are critical for cell and tissue homeostasis. Traditional genetic and biochemical approaches have shed light on basic principles underlying these processes. However, the list of factors required for secretory pathway function remains incomplete, and mechanis...

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Detalles Bibliográficos
Autores principales: Bassaganyas, Laia, Popa, Stephanie J., Horlbeck, Max, Puri, Claudia, Stewart, Sarah E., Campelo, Felix, Ashok, Anupama, Butnaru, Cristian M., Brouwers, Nathalie, Heydari, Kartoosh, Ripoche, Jean, Weissman, Jonathan, Rubinsztein, David C., Schekman, Randy, Malhotra, Vivek, Moreau, Kevin, Villeneuve, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829651/
https://www.ncbi.nlm.nih.gov/pubmed/31488582
http://dx.doi.org/10.1083/jcb.201902028

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