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Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes

In patients with inactivating mutations in myosin Vb (Myo5B), enterocytes show large inclusions lined by microvilli. The origin of inclusions in small-intestinal enterocytes in microvillus inclusion disease is currently unclear. We postulated that inclusions in Myo5b KO mouse enterocytes form throug...

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Detalles Bibliográficos
Autores principales: Engevik, Amy C., Kaji, Izumi, Postema, Meagan M., Faust, James J., Meyer, Anne R., Williams, Janice A., Fitz, Gillian N., Tyska, Matthew J., Wilson, Jean M., Goldenring, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829668/
https://www.ncbi.nlm.nih.gov/pubmed/31562230
http://dx.doi.org/10.1083/jcb.201902063