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Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes
In patients with inactivating mutations in myosin Vb (Myo5B), enterocytes show large inclusions lined by microvilli. The origin of inclusions in small-intestinal enterocytes in microvillus inclusion disease is currently unclear. We postulated that inclusions in Myo5b KO mouse enterocytes form throug...
Autores principales: | Engevik, Amy C., Kaji, Izumi, Postema, Meagan M., Faust, James J., Meyer, Anne R., Williams, Janice A., Fitz, Gillian N., Tyska, Matthew J., Wilson, Jean M., Goldenring, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829668/ https://www.ncbi.nlm.nih.gov/pubmed/31562230 http://dx.doi.org/10.1083/jcb.201902063 |
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